| 2005 | Stay | Ne‐Yo | 3 | 1 |
| 2005 | So Sick | Ne‐Yo | 1 | 5 |
| 2006 | Sexy Love | Ne‐Yo | 5 | 4 |
| 2007 | Because of You | Ne‐Yo | 4 | 4 |
| 2007 | Sexual Healing | Sarah Connor feat. Ne‐Yo | | 1 |
| 2007 | Can We Chill | Ne‐Yo | 3 | 1 |
| 2007 | Hate That I Love You | Rihanna feat. Ne‐Yo | 4.5 | 1 |
| 2008 | Finer Things | DJ Felli Fel feat. Kanye West, Jermaine Dupri, Fabolous & Ne‐Yo | | 1 |
| 2008 | Can We Chill / Spotlight | Ne‐Yo | 4 | 1 |
| 2008 | Closer | Ne‐Yo | 3 | 4 |
| 2008 | Miss Independent | Ne‐Yo | 2 | 1 |
| 2008 | She Got Her Own | Ne‐Yo | 4 | 1 |
| 2008 | Mad | Ne‐Yo | | 3 |
| 2009 | Knock You Down | Keri Hilson feat. Kanye West & Ne‐Yo | | 4 |
| 2009 | Never Knew I Needed (From "The Princess and the Frog") | Ne‐Yo | 3 | 2 |
| 2010 | Beautiful Monster | Ne‐Yo | 4 | 1 |
| 2010 | Amazing You | Ne‐Yo | 4 | 2 |
| 2010 | One In a Million | Ne‐Yo | 1 | 1 |
| 2010 | Angel - Stranger | Ne‐Yo | 1 | 1 |
| 2010 | Beautiful Monster & Champagne Life | Ne‐Yo | | 1 |
| 2011 | Give Me Everything | Pitbull feat. Ne‐Yo, Afrojack & Nayer | 4.5 | 3 |
| 2011 | We Can't Stop | jj feat. Ne‐Yo | | 1 |
| 2011 | The Way You Move | Ne‐Yo feat. Trey Songz & T‐Pain | 2 | 1 |
| 2012 | Think Like a Man | Jennifer Hudson & Ne‐Yo feat. Rick Ross | 3 | 1 |
| 2012 | Let’s Go | Calvin Harris feat. Ne‐Yo | 2 | 2 |
| 2012 | Lazy Love | Ne‐Yo | 3 | 1 |
| 2012 | Betta Love Me (Right) | Ne‐Yo | 2 | 1 |
| 2012 | Let Me Love You (Until You Learn to Love Yourself) | Ne‐Yo | 5 | 2 |
| 2012 | Play Hard | David Guetta feat. Ne‐Yo & Akon | 5 | 4 |
| 2013 | Tonight | Jessica Sanchez feat. Ne‐Yo | 3 | 1 |
| 2013 | You Girl | Shaggy feat. Ne‐Yo | | 1 |
| 2014 | Incredible | Céline Dion with Ne‐Yo | | 1 |
| 2014 | A House Is Not a Home | Dionne Warwick featuring Ne‐Yo | | 1 |
| 2014 | Money Can’t Buy | Ne‐Yo feat. Jeezy | 3 | 1 |
| 2014 | She Knows | Ne‐Yo | 3 | 2 |
| 2014 | Time of Our Lives | Pitbull & Ne‐Yo | | 1 |
| 2015 | Every Day With Love | Ne‐Yo feat. Sonna Rele | | 1 |
| 2015 | Friend Like Me (From "Aladdin") | Ne‐Yo | | 1 |
| 2016 | Please Stay | Alpha Dream featuring Ne‐Yo & Snoop Dogg | | 1 |
| 2016 | Sin miedo | Yunel, Ne‐Yo & J.Álvarez | | 1 |
| 2017 | Another Love Song | Ne‐Yo | | 1 |
| 2018 | GOOD MAN | Ne‐Yo | | 1 |
| 2018 | Push Back | Ne‐Yo, Bebe Rexha & Stefflon Don | | 2 |
| 2019 | Unlove You | Armin van Buuren feat. Ne‐Yo | | 1 |
| 2020 | Me quedaré contigo | Pitbull & Ne‐Yo ft. Lenier & El Micha | | 1 |
| 2020 | Pinky Ring | Ne‐Yo & O.T. Genasis | | 1 |
| 2020 | Over Again | Charly Black & Ne‐Yo | | 1 |
| 2020 | U 2 Luv | Ne‐Yo & Jeremih | | 1 |
| 2020 | Change | Jermaine Dupri, Ne‐Yo, Johntá Austin, Common, Gary Clark Jr., Eric Bellinger, Rotimi, Detroit Youth Choir, PJ Morton, Smokie Norful, Wanya Morris, Big Rube, Bryan‐Michael Cox, Anthony Hamilton, Keedron Bryant, Kirk Franklin & Jac Ross | 5 | 1 |
| 2020 | Because Of You (Remix) | Ne‐Yo | | 1 |
| 2020 | U 2 Luv (Remix) | Ne‐Yo | | 1 |
| 2021 | Shake | L.L.A.M.A,, Ne‐Yo & Carmen DeLeon | | 1 |
| 2021 | Pretend | Kamarah J. & Ne‐Yo | | 1 |
| 2021 | No Plans for Love | D‐Nice with Ne‐Yo & Kent Jones | | 1 |
| 2021 | “One Headlight” | Frank Niebauer & Ne‐Yo | | 1 |
| 2021 | Raider Colors | Too $hort, Ice Cube, Ne‐Yo, DJ Nina 9, Rayven Justice | | 1 |
| 2021 | What If | Ne‐Yo | | 2 |
| 2021 | Let Me Go | Benny Benassi feat. Ne‐Yo | | 2 |
| 2021 | Kiss Me It’s Christmas | Leona Lewis featuring Ne‐Yo | | 3 |
| 2021 | Stay Down | Ne‐Yo | | 1 |
| 2022 | Bad Habits | Ne‐Yo | | 1 |
| 2022 | FriendZone | DJ Moss.irie, Ne‐Yo & DJ CandyLips | | 1 |
| 2022 | Never Settle | Ne‐Yo | | 1 |
| 2022 | Don't Love Me - A COLORS SHOW | Ne‐Yo | | 1 |
| 2022 | Step Up: Season 3, Episode 1 (Original Soundtrack) | Ne‐Yo, Stephanie Economou & EmmoLei Sankofa | | 1 |
| 2023 | Mexico | Dimitri Vegas & Like Mike, Ne‐Yo & Danna Paola | | 1 |
| 2023 | Link Up | Ne‐Yo | | 1 |
| 2023 | Link Up (remix) | Ne‐Yo & Fabolous | | 1 |
| 2024 | Sage | Eric Bellinger & Ne‐Yo | | 1 |
| 2024 | 2 The Moon | Pitbull, Ne‐Yo, AFROJACK & DJ Buddha | | 1 |
| 2024 | 2 Million Secrets | Ne‐Yo | | 1 |
| 2024 | Show Me | Ne-Yo | | 1 |
| — | Turn all The Lights On | T‐Pain feat. Ne‐Yo | | 0 |
Play on ListenBrainz