| 2010 | I'm on It | French Montana feat. Big Sean, Nipsey Hussle & Wiz Khalifa | | 1 |
| 2010 | What U Doin? | Big Sean | | 1 |
| 2010 | Good Friday | Kanye West feat. Common, Pusha T, Kid Cudi, Big Sean & Charlie Wilson | | 1 |
| 2010 | Don't Look Down | Kanye West feat. Mos Def, Lupe Fiasco & Big Sean | 3 | 1 |
| 2010 | Looking for Trouble | Kanye West feat. Pusha T, CyHi da Prynce, Big Sean & J. Cole | 4 | 1 |
| 2011 | My Last | Big Sean feat. Chris Brown | | 2 |
| 2011 | I Do It | Big Sean | | 2 |
| 2011 | Marvin & Chardonnay | Big Sean feat. Kanye West & Roscoe Dash | | 1 |
| 2011 | Dance (A$$) | Big Sean feat. Nicki Minaj | | 2 |
| 2012 | Mercy | Kanye West feat. Big Sean, Pusha T & 2 Chainz | | 1 |
| 2012 | Till I Die | Chris Brown feat. Big Sean & Wiz Khalifa | | 1 |
| 2012 | My Homies Still | Lil Wayne feat. Big Sean | | 1 |
| 2012 | As Long as You Love Me | Justin Bieber feat. Big Sean | 5 | 2 |
| 2012 | Clique | Kanye West, Jay‐Z & Big Sean | | 1 |
| 2012 | Burn | Meek Mill feat. Big Sean | | 1 |
| 2012 | Guap | Big Sean | | 1 |
| 2013 | Switch Up | Big Sean feat. Common | | 1 |
| 2013 | Wild | Jessie J ft. Dizzee Rascal & Big Sean | | 10 |
| 2013 | Beware | Big Sean feat. Lil Wayne & Jhené Aiko | | 1 |
| 2013 | Right There | Ariana Grande feat. Big Sean | 5 | 3 |
| 2013 | Control | Big Sean feat. Kendrick Lamar & Jay Electronica | | 1 |
| 2013 | Sorry | Naya Rivera feat. Big Sean | | 1 |
| 2013 | Top of the World | Mike Posner feat. Big Sean | | 1 |
| 2014 | 1st Quarter | Big Sean | | 1 |
| 2014 | Memphis | Justin Bieber feat. Big Sean | 5 | 1 |
| 2014 | Don't Play | Travi$ Scott feat. The 1975 & Big Sean | | 1 |
| 2014 | 4th Quarter | Big Sean | | 1 |
| 2014 | Jit Juke | Big Sean | | 1 |
| 2014 | I Don’t Fuck With You | Big Sean | | 1 |
| 2014 | Open Wide | Calvin Harris feat. Big Sean | | 1 |
| 2014 | Alright | Logic featuring Big Sean | | 1 |
| 2015 | Blessings | Big Sean | | 2 |
| 2015 | Me, Myself and I | Big Sean | | 1 |
| 2015 | B Boy | Meek Mill feat. Big Sean & A$AP Ferg | | 1 |
| 2015 | How Many Times | DJ Khaled, Chris Brown, Lil Wayne & Big Sean | | 1 |
| 2015 | Back Up | DeJ Loaf feat. Big Sean | | 1 |
| 2015 | What a Year | Big Sean | | 1 |
| 2016 | World Is Mine | A$AP Ferg feat. Big Sean | | 1 |
| 2016 | Champions | Kanye West, Gucci Mane, Big Sean, 2 Chainz, Travis Scott, Yo Gotti, Quavo & Desiigner | | 1 |
| 2016 | Bounce Back | Big Sean | | 1 |
| 2016 | No More Interviews | Big Sean | | 1 |
| 2016 | Living Single | Big Sean feat. Chance the Rapper & Jeremih | | 1 |
| 2016 | Moves | Big Sean | | 1 |
| 2017 | Halfway Off the Balcony | Big Sean | | 1 |
| 2017 | I Think of You | Jeremih feat. Chris Brown & Big Sean | | 2 |
| 2017 | Skateboard P | MadeinTYO feat. Big Sean | | 2 |
| 2017 | On the Come Up | Mike WiLL Made-It feat. Big Sean | | 1 |
| 2017 | Feels | Calvin Harris feat. Pharrell Williams, Katy Perry & Big Sean | | 3 |
| 2018 | Big Bank | YG feat. 2 Chainz, Big Sean & Nicki Minaj | | 2 |
| 2019 | Balance | Icewear Vezzo feat. Big Sean | | 1 |
| 2019 | Jealous | DJ Khaled feat. Chris Brown, Lil Wayne & Big Sean | | 1 |
| 2019 | Ready Set | Kash Doll & Big Sean | | 1 |
| 2019 | Overtime | Big Sean | | 1 |
| 2019 | Single Again | Big Sean | | 4 |
| 2019 | Bezerk | Big Sean feat. A$AP Ferg & Hit‐Boy | | 8 |
| 2019 | None of Your Concern | Jhené Aiko feat. Big Sean | | 2 |
| 2020 | Deep Reverence | Big Sean feat. Nipsey Hussle | | 1 |
| 2020 | 4 Thangs | Freddie Gibbs feat. Big Sean & Hit‐Boy | | 2 |
| 2020 | Salute | Hit‐Boy feat. Big Sean and Fivio Foreign | | 1 |
| 2020 | Way Out | Jack Harlow feat. Big Sean | | 1 |
| 2021 | Little While | Sada Baby feat. Big Sean & Hit‐Boy | 5 | 1 |
| 2021 | It Ain’t My Fault | Babyface Ray, Big Sean & Hit‐Boy | | 1 |
| 2021 | What a Life | Big Sean & Hit‐Boy | | 8 |
| 2022 | Hate Our Love | Queen Naija & Big Sean | | 8 |
| 2022 | Easy Lover | Ellie Goulding ft. Big Sean | | 3 |
| 2022 | Common | Quinn XCII with Big Sean | | 3 |
| 2023 | Palisades, CA | Larry June, The Alchemist & Big Sean | | 1 |
| 2024 | Precision | Big Sean | | 1 |
| 2024 | SHUT UP | Jessie Reyez x Big Sean | | 1 |
| 2024 | Tobey | Eminem, Big Sean & BabyTron | | 3 |
| 2024 | Yes | Big Sean | | 1 |
| 2024 | Ya Don’t Stop | DJ Premier, Lil Wayne, Rick Ross & Big Sean | | 1 |
