MusicIP Mixer is a program by AmpliFIND (formerly MusicIP) that has features used to analyze music files to generate PUIDs on the MusicDNS servers, amongst other added value "end user" features (recommending similar music, building playlists etc)
The software is available for download at 
There is a 'lite' command line version of the PUID generating features of MMM named genpuid available. It can be used to generate and submit the appropriate info to create a new PUID without all the music library stuff. Music Analysis cannot be integrated into the Picard Tagger, because the process is closed source and Picard is GPLed.